Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism).

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Waking genioglossal electromyogram in sleep apnea patients versus normal controls (a neuromuscular compensatory mechanism).

Pharyngeal collapse in obstructive sleep apnea patients is likely a product of a sleep-related decrement in pharyngeal dilator muscle activity superimposed upon abnormal airway anatomy. We postulate that during wakefulness, increased pharyngeal dilator muscle activity in apnea patients compensates for diminished airway size thus maintaining patency. We studied the waking genioglossus (GG) elect...

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Effect of posture and breathing route on genioglossal electromyogram activity in normal subjects and in patients with the sleep apnea/hypopnea syndrome.

Patients with the sleep apnea/hypopnea syndrome (SAHS) often have more apneas supine that sitting. We have shown radiologically that although the retropalatal airway narrows on lying down, the retroglossal airway widens. We have thus investigated the effect of posture on genioglossal EMG activity in 10 normal subjects and 10 patients with SAHS (58 +/- 29 SD apneas + hypopneas/h) using peroral i...

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Sleep Apnea in Patients with Stroke and Related Risk Factors

  Background and Objectives: Sleep apnea involves repetitive cycles of obstructive sleep that disrupt sleep. This complication is the most important modifiable risk factors for stroke. The aim of this study was to assess sleep apnea in patients with stroke.    Material and Methods: In this cross-sectional study, 132 patients with stroke were recruited using convenience samplin...

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Cone-beam CT analysis of patients with obstructive sleep apnea compared to normal controls

PURPOSE To evaluate the upper airway dimensions of obstructive sleep apnea (OSA) and control subjects using a cone-beam computed tomography (CBCT) unit commonly applied in clinical practice in order to assess airway dimensions in the same fashion as that routinely employed in a clinical setting. MATERIALS AND METHODS This was a retrospective analysis utilizing existing CBCT scans to evaluate ...

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A possible mechanism for mixed apnea in obstructive sleep apnea.

Hypopneas or pauses in respiratory effort frequently precede episodes of obstructive sleep apnea resulting in mixed apneas. We studied five subjects after chronic tracheostomy for obstructive sleep apnea. During stable non-REM (NREM) sleep, subjects breathed entirely through the tracheostomy. Tracheostomy occlusion caused experimental obstructive apnea which lasted 13.9 +/- 4.7 sec and ended wi...

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ژورنال

عنوان ژورنال: Journal of Clinical Investigation

سال: 1992

ISSN: 0021-9738

DOI: 10.1172/jci115751